Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients

The 1982 revised criteria for the classification of systemic lupus erythematosus

Eng M. Tan, Alan S. Cohen, James F. Fries et al. · Arthritis & Rheumatism · 1982 · 14.6K citations

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Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

John B. Harley, Marta E. Alarcón‐Riquelme, Lindsey A. Criswell et al. · Nature Genetics · 2008 · 1.3K citations

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Difference in disease features between childhood‐onset and adult‐onset systemic lupus erythematosus

Hermine I. Brunner, Dafna D. Gladman, Dominique Ibañez et al. · Arthritis & Rheumatism · 2008 · 556 citations

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Characterization of a Soluble Cytoplasmic Antigen Reactive with Sera from Patients with Systemic Lupus Erythmatosus

Geoffrey E. Clark, Morris Reichlin, Thomas B. Tomasi · The Journal of Immunology · 1969 · 503 citations · Full text

Life Sciences, Biochemistry, Immunology +13

Three functional variants of IFN regulatory factor 5 ( <i>IRF5</i> ) define risk and protective haplotypes for human lupus

Robert Graham, Chieko Kyogoku, Irina Vlasova-St. Louis et al. · Proceedings of the National Academy of Sciences · 2007 · 456 citations · Full text

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