Decreased<i>N</i>⁶-Methyladenosine in Peripheral Blood RNA From Diabetic Patients Is Associated With<i>FTO</i>Expression Rather Than<i>ALKBH5</i>

Abstract

These data suggest that the increased mRNA expression of FTO could be responsible for the reduction of m(6)A in T2DM, which may further increase the risk of complications of T2DM. Low m(6)A should be investigated further as a novel potential biomarker of T2DM.