Concepedia

Publication | Open Access

Complement Factor H Polymorphism, Complement Activators, and Risk of Age-Related Macular Degeneration

DOIFull Paper Access

346

Citations

35

References

2006

Year

Dominiek D. G. Despriet, Caroline C. W. Klaver, Jacqueline C.M. Witteman, Arthur A. Bergen, Isabella Kardys, Moniek P.M. de Maat, Sharmila S. Boekhoorn, Johannes R. Vingerling, Albert Hofman, Ben A. Oostra,
JAMA

Abstract

The CFH Y402H polymorphism may account for a substantial proportion of AMD in individuals similar to those in the Rotterdam Study and may confer particular risk in the presence of environmental and genetic stimulators of the complement cascade.

References

YearCitations

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