Oral Treatment of Pernicious Anaemia: First Fifty Cases

Abstract

* Consultant Pathologist, St. Helens Hospital, St. Helens, t Reader in Biochemistry, Royal College of Advanced Technology, Salford. was 86%, the P.C.V. 38%, and the serum vitamin-Bi_ level 40 /^g./ ml. A marrow puncture at this time showed megaloblastic changes in approximately 40% of the red-cell series. No abnormal signs were detected. The daily dose was therefore increased to 40 /?g. of peptide complex, and by the 2,260th day the symptoms had disappeared, the blood picture had improved slightly, and the marrow had reverted to normal. The serum vitamin-Bi2 level,