Cabazitaxel in patients with advanced solid tumours: Results of a Phase I and pharmacokinetic study

Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial

Johann S. de Bono, Stéphane Oudard, Mustafa Özgüroğlu et al. · The Lancet · 2010 · 3.3K citations

Medicine, Oncology, Pharmacology +16

Accelerated Titration Designs for Phase I Clinical Trials in Oncology

Richard Simon, Larry Rubinstein, Susan G. Arbuck et al. · JNCI Journal of the National Cancer Institute · 1997 · 640 citations · Full text

Medicine, Oncology, Pharmacology +17

Functional expression of P-glycoprotein in apical membranes of human intestinal Caco-2 cells. Kinetics of vinblastine secretion and interaction with modulators

Janice Hunter, Mark A. Jepson, T Tsuruo et al. · Journal of Biological Chemistry · 1993 · 367 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Phase I and Pharmacokinetic Study of XRP6258 (RPR 116258A), a Novel Taxane, Administered as a 1-Hour Infusion Every 3 Weeks in Patients with Advanced Solid Tumors

Alain C. Mita, Louis Denis, Eric K. Rowinsky et al. · Clinical Cancer Research · 2009 · 332 citations

Medicine, Oncology, Pharmacology +16

A population pharmacokinetic model for docetaxel (Taxotere®): Model building and validation

René Bruno, Nicole Vivier, J. Vergniol et al. · Journal of Pharmacokinetics and Biopharmaceutics · 1996 · 265 citations

Pharmacy, Pharmacokinetics, Pharmacology +14