Publication | Closed Access
Asymmetric reduction of aromatic ketones by sodium borohydride in the presence of bovine serum albumin
34
Citations
0
References
1978
Year
EngineeringBiochemistryChiral TemplateMedicineBioanalysisAromatic KetonesProduct AlcoholsOrganic ChemistryAnalytical ChemistryBovine Serum AlbuminClinical ChemistrySodium BorohydridePharmacologyAsymmetric CatalysisEnantioselective SynthesisNatural Product Synthesis
Bovine serum albumin was used to provide a chiral template for asymmetric reduction of aromatic ketones by the achiral NaBH4, and substantial (20–80%) enantiomeric excesses were obtained in the product alcohols.