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Design and synthesis of new derivatives of 3<i>H‐</i>quinazolin‐4‐one as potential anticonvulsant agents
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References
2011
Year
Derivative (Chemistry)Potential Anticonvulsant AgentsDerivativesEngineeringMaximal Electroshock MethodPharmaceutical ChemistryNew DerivativesMedicineHeterocyclicOrganic ChemistryChemistryHeterocycle ChemistryAnticonvulsant ActivityPharmacologySystematic InvestigationBiomolecular EngineeringDrug Discovery
Abstract As a part of systematic investigation on synthesis and biological activities, some new derivatives of 2‐ethyl‐3‐(substituted benzothiazole‐2′‐yl)–[3 H ]‐quinazolin‐4‐ones 3 have been synthesized, and the structures of the compounds were confirmed by elemental analysis and spectral data. The newly synthesized derivatives are then screened for anticonvulsant activity by maximal electroshock method. J. Heterocyclic Chem., (2011).
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