DRESS Syndrome: A Practical Approach for Primary Care Practitioners

Abstract

Drug rash with eosinophilia and systemic symptoms (DRESS), also called as drug hypersensitivity syndrome (DHS)/antiepileptic drug hypersensitivity syndrome, is a severe form of cutaneous drug reaction and is characterized by fever, skin rash, lymphadenopathy, hematological abnormalities, and internal organ involvement. In this case report, we present a child who developed DRESS with peripheral eosinophilia and hepatic involvement subsequent to the use of carbamazepine and who responded very well to systemic corticosteroids.