Microfluidic Multicolor Encoding of Microspheres with Nanoscopic Surface Complexity for Multiplex Immunoassays

Abstract

Technicolor dreamcoating: A microfluidic device produces and manipulates double-emulsion droplets of equal size with unprecedented controllability (see picture). The droplets, which contain color core droplets, are photopolymerized to produce transparent microspheres. Silica colloidal particles anchored preferentially at the surfaces of the microspheres provide efficient binding sites for biomolecules for biological analyses. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.