Publication | Closed Access
Asymmetric Synthesis of α‐Amino Acids under Operationally Convenient Conditions
41
Citations
58
References
2014
Year
BiosynthesisEngineeringBiochemistryNatural SciencesDiversity-oriented SynthesisAsymmetric SynthesisOrganic ChemistryPeptide ScienceVarious Amino AcidsGeneral Asymmetric SynthesisStereoselective SynthesisAsymmetric CatalysisChiral ReagentEnantioselective SynthesisBiomolecular Engineering
Abstract A new multipurpose glycine equivalent for the general asymmetric synthesis of α‐amino acids is introduced. The chiral reagent can be transformed to various amino acids by alkylations with alkyl halides as well as aldol and Michael addition reactions under operationally convenient reaction conditions at room temperature with virtually complete stereochemical control. magnified image
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