Journal of Medical Microbiology · 1991 · 18 citations · 12 references
MedicineInfectious DiseasesMicrobiologyDiagnostic MicrobiologyMedical MicrobiologyMolecular DiagnosticsCulture TechniquesDiagnostic BacteriologyGynecologic InfectionsInfectious Disease Molecular TestingSexually Transmitted Infection DiagnosticsSexually Transmitted InfectionsDiagnosis Of Cervical InfectionDna Probe AssaysPositive Predictive ValuePositive Predictive Value AnalysisSexually Transmitted Infection Diagnosis
A new DNA probe assay (PACE 2, Gen-probe) was compared with cell culture for the detection of Chlamydia trachomatis in 909 women attending the Royal Women's Hospital, Melbourne, Victoria. The DNA probe assay had a sensitivity of 86.2%, a specificity of 99.9% and a positive predictive value of 96.2% in a population with 3.2% prevalence, indicating that it may be a suitable alternative to culture for the detection of C. trachomatis in specimens from the genital tract.
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Max Chernesky, James B. Mahony, Santina Castriciano et al. · The Journal of Infectious Diseases · 1986 · 149 citations
Molecular techniques for the detection of Chlamydia trachomatis
Ellena M. Peterson, R Oda, Richard Alexander et al. · Journal of Clinical Microbiology · 1989 · 43 citations · Full text