Concepedia

Novel Immunoassay for Quantification of Brain Natriuretic Peptide and Its Precursor in Human Blood

Natalia N Tamm, Karina R Seferian, Alexander G Semenov, Kadriya S Mukharyamova, Ekaterina V Koshkina, Mihail I Krasnoselsky, Alexander B. Postnikov, Daria V. Serebryanaya, Fred S. Apple, MaryAnn M Murakami,

Clinical Chemistry · 2008 · 38 citations · 14 references

DOI

Abstract

We have developed this sensitive single-epitope sandwich assay for detecting BNP, proBNP, and their fragments in human blood. This assay appears promising for use in clinical studies to assist in triage, management, and outcomes assessment in heart failure patients.

References

14

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Evidence for Functional Heterogeneity of Circulating B-Type Natriuretic Peptide

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Quality Specifications for B-Type Natriuretic Peptide Assays

Fred S. Apple · Clinical Chemistry · 2005 · 181 citations · Full text