CpG Island M`ethylation Status in Gastric Carcinoma with and without Infection of Epstein-Barr Virus

Abstract

The methylation profile of five representative genes is useful to stratify gastric carcinomas into biologically different subgroups. EBV-associated gastric carcinoma showed global CpG island methylation, comprising a pathogenetically distinct subgroup in CIMP-H gastric carcinoma.