The impact of antibiotic use on the incidence and resistance pattern of extended‐spectrum beta‐lactamase‐producing bacteria in primary and secondary healthcare settings

Abstract

This study supports the value of restricting the use of certain antimicrobial classes to control ESBL, and demonstrates the feasibility of reversing resistance patterns post successful antibiotic restriction. The study also highlights the potential value of the time-series analysis in designing efficient antibiotic stewardship.