Reproduction · 1968 · 12 citations · 8 references
Life SciencesObstetricsVeterinary PhysiologyMaternal-fetal MedicineReproductive MedicineReproductive PhysiologyMaternal-fetal PhysiologyPlacental PhysiologyPregnancy PhysiologyUterotonic TherapyVasopressor TherapyBlood Flow Changes During PregnancyContrastPlacental Blood FlowPlacental VasculatureUterine AnatomyUterine PhysiologyUteroplacental CirculationVasopressin Pharmacology
Summary. The effect of vasopressin on the flow of blood through the uterus and placenta in the rabbit has been investigated by an angio-graphic technique, with contrast injection through a catheter inserted in the external iliac artery or selectively in the urogenital artery. It was found that the drug markedly reduced contrast filling of the vessels in the placentae and uterine wall including the placental sinuses. It is suggested that this effect was produced by constriction of the venules in the uterine vascular bed. The possible operation of a shunt mechanism in the uterus is discussed.
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