Room Temperature Nickel(II) Complexes [(4‐MeOC₆H₄)Ni(PCy₃)₂OTs and Ni(PCy₃)₂X₂]‐Catalyzed Cross‐Coupling Reactions of Aryl/Alkenyl Sulfonates with Arylboronic Acids

Abstract

Abstract Room temperature nickel(II) complexes [(4‐MeOC 6 H 4 )Ni(PCy 3 ) 2 OTs and Ni(PCy 3 ) 2 X 2 (X=Cl, Br)]‐catalyzed cross‐coupling reactions of aryl/alkenyl sulfonates with arylboronic acids are described. The nickel(II) complex (4‐MeOC 6 H 4 )Ni(PCy 3 ) 2 OTs proved to be a general catalyst for the Suzuki–Miyaura cross‐coupling reactions of aryl sulfonates with arylboronic acids. By limiting the amount of the water in the initial catalytically active Ni(0) species generation stage, Ni(PCy 3 ) 2 X 2 (X=Cl, Br) could also be efficient catalysts for the cross‐coupling reactions a variety of aryl/activated alkenyl tosylates with arylboronic acids. The mild reaction condition, the easy availability of the catalysts and excellent coupling yields make these catalyst systems potentially useful in organic synthesis.