Synthesis of a [6-Pyridinyl-18F]-labelled fluoro derivative of WAY-100635 as a candidate radioligand for brain 5-HT1A receptor imaging with PET

Efficient stereospecific synthesis of no-carrier-added 2-[18F]-fluoro-2-deoxy-D-glucose using aminopolyether supported nucleophilic substitution.

K. Hamacher, Heinz H. Coenen, G. Stöcklin · PubMed · 1986 · 1.4K citations

Synthesis Time, Nucleophilic Fluorination, Medicinal Chemistry +13

Brain Serotonin1A Receptor Binding Measured by Positron Emission Tomography With [11C]WAY-100635

Peter A. Sargent, Christopher J. Bench, Eugenii A. Rabiner et al. · Archives of General Psychiatry · 2000 · 639 citations

Exquisite delineation of 5-HT1A receptors in human brain with PET and [carbonyl-11C]WAY-100635

Victor W. Pike, Julie A. McCarron, Adriaan A. Lammertsma et al. · European Journal of Pharmacology · 1996 · 225 citations

Functional Selectivity, Neuroanatomy, 5-Ht1a Receptors +8

High-Yield Radiosynthesis and Preliminary In Vivo Evaluation of p-[18F]MPPF, a Fluoro Analog of WAY-100635

Didier Le Bars, Christian Lemaire, Nathalie Ginovart et al. · Nuclear Medicine and Biology · 1998 · 139 citations

Vivo Evaluation, Fluoro Analog, Fluorous Synthesis +6

Synthesis and Nicotinic Acetylcholine Receptor in Vivo Binding Properties of 2-Fluoro-3-[2(<i>S</i>)-2-azetidinylmethoxy]pyridine: A New Positron Emission Tomography Ligand for Nicotinic Receptors

Frédéric Dollé, Lilian Dolci, Héric Valette et al. · Journal of Medicinal Chemistry · 1999 · 125 citations · Full text

Pharmacotherapy, New Series, Lead Compound +18