Concepedia

Publication | Open Access

HMGCoA reductase inhibition reverses myocardial fibrosis and diastolic dysfunction through AMP-activated protein kinase activation in a mouse model of metabolic syndrome

DOIFull Paper Access

74

Citations

38

References

2013

Year

Nerea Hermida, Andreas Markl, Julien Hamelet, Tim Van Assche, Annelies Vanderper, Paul Herijgers, Marc van Bilsen, Denise Hilfiker‐Kleiner, Gauthier Noppe, Christophe Beauloye,
Cardiovascular Research

Abstract

In this model of MS, statin treatment reverses myocardial remodelling and improves ventricular relaxation through AMPK-mediated anti-fibrotic effects.

References

YearCitations

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