Publication | Closed Access
Efficient One‐Pot Friedel–Crafts Acylation of Benzene and its Derivatives with Unprotected Aminocarboxylic Acids in Polyphosphoric Acid
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Citations
18
References
2006
Year
Polyphosphoric AcidAntitumor ActivityEngineeringOrganic Chemistry4‐Aminophenylacetic AcidsUnprotected Aminocarboxylic AcidsChemistryPharmaceutical ChemistryMedicinal ChemistryPolymer ChemistryDerivativesDiversity-oriented SynthesisFriedel–crafts ReactionPharmacologyNatural Product SynthesisBiomolecular EngineeringNatural SciencesPolymer SciencePolymer ReactionSynthetic ChemistryPolymer Synthesis
Abstract A number of aminobenzophenones have been synthesized by acylation of benzene and its derivatives with different 2‐,3‐,4‐aminobenzoic and 4‐aminophenylacetic acids in polyphosphoric acid via Friedel–Crafts reaction as compounds with expected antitumor activity.
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