Concepedia

Efficient One‐Pot Friedel–Crafts Acylation of Benzene and its Derivatives with Unprotected Aminocarboxylic Acids in Polyphosphoric Acid

Iliyan Ivanov, Stoyanka Nikolova, Stela Statkova‐Abeghe

Synthetic Communications · 2006 · 22 citations · 18 references

DOI

Concepts

Abstract

Abstract A number of aminobenzophenones have been synthesized by acylation of benzene and its derivatives with different 2‐,3‐,4‐aminobenzoic and 4‐aminophenylacetic acids in polyphosphoric acid via Friedel–Crafts reaction as compounds with expected antitumor activity.

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