Healing Characteristics of Free and Pedicle Fat Grafts after Dorsal Laminectomy and Durotomy in Dogs

Abstract

Dorsal laminectomy and durotomy were performed at thoracic vertebrae 12 and 13 (T12‐T13) and lumbar vertebrae 1 and 2 (L1–L2) in 12 normal dogs. A free fat graft harvested from subcutaneous tissue adjacent to the incision was placed over the T12–T13 laminectomy site. A 75 × 25 × 5 mm pedicle fat graft harvested from a similar location was placed over the L1–L2 laminectomy site. Three dogs each were euthanatized at weeks 2, 4, 8, and 16. With both types of fat grafts, an initial inflammatory stage reduced the size of the graft approximately 50%. Axonal degeneration and demyelination of the spinal cord resolved by week 16. At week 16, the durotomy sites had healed, but the dura mater was adhered to the spinal cord. No difference between the grafts could be demonstrated by antemortem myelography and cerebrospinal fluid analysis. There was no demonstrable advantage to the use of pedicle fat grafts.