Concepedia

A randomized, controlled trial of simvastatin versus rosuvastatin in patients with acute myocardial infarction: the Secondary Prevention of Acute Coronary Events – Reduction of Cholesterol to Key European Targets Trial

Alistair S. Hall, Beryl M. Jackson, Amanda Farrin, Maria Efthymiou, Julian H. Barth, Joanne Copeland, Kristian Bailey, Simon P.R. Romaine, Anthony J. Balmforth, Terry McCormack,

European Journal of Cardiovascular Prevention & Rehabilitation · 2009 · 25 citations · 31 references

DOIFull text

Open access

Abstract

We observed no superiority of either treatment for the ESC-03 lipid targets. Rosuvastatin 10 mg lowered mean cholesterol more effectively than simvastatin and achieved better results for the latest, more stringent, ESC target.

References

31

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Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)

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Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)

Anders Olsson, John J.V. McMurray, G Thorgeirsson et al. · The Lancet · 1994 · 8.5K citations

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The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels

Frank M. Sacks, Marc A. Pfeffer, Lemuel A. Moyé et al. · New England Journal of Medicine · 1996 · 7.5K citations · Full text

MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial

The Lancet · 2002 · 7K citations

, , +10