A Convergent Synthesis of <i>N</i>‐Glycopeptides

Abstract

Two birds are killed with one stone when N-glycopeptides are synthesized by condensation of photoreactive peptides with glycosylamines. Firstly, the aspartic acid side chain is protected as an amide with a nitroindoline moiety, which is then converted into a powerful acylating agent by UV light. Secondly, photoacylation is carried out under base-free conditions, which minimizes an undesired side reaction, the formation of aspartimide. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z502687_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.