Journal of the Chemical Society Chemical Communications · 1989 · 42 citations · 0 references
Life SciencesBiochemistryPlant BiologyMetabolismNatural Product BiosynthesisPlant BiochemistryFungal Natural Product BiosynthesisFungal Toxin BiosynthesisMicrobial Natural Product BiosynthesisPhenylpropanoid BiosynthesisPlant Natural Product BiosynthesisToxin ProductionAlternaria MycotoxinsAlternaria Toxin BiosynthesisAromatic Compound BiosynthesisBiosynthetic Enzyme CharacterizationBiosynthetic Pathway ElucidationChemical LabellingMethionine BiosynthesisPhytoalexin Biosynthesis
The building blocks and the origin of hydrogen and oxygen atoms in solanapyrone A (1) were determined by incorporation experiments employing sodium [1-13C]-, [1,2-13C2]-, [1-13C, 18O2]-, [1-13C, 2H3]-, [2-13C, 2H3]acetates and [S-13CH3] methionine; the labelling pattern supports the hypothesis that (1) is biosynthesized via the intramolecular Diels–Alder reaction.