Tandem Catalytic C(sp³)H Amination/Sila‐Sonogashira–Hagihara Coupling Reactions with Iodine Reagents

Abstract

A new tandem C-N and C-C bond-forming reaction has been achieved through Rh(II) /Pd(0) catalysis. The sequence first involves an iodine(III) oxidant, then the in situ generated iodine(I) by-product is used as a coupling partner. The overall process demonstrates the synthetic value of iodoarenes produced in trivalent iodine reagent mediated oxidations.