Caco‐2 versus Caco‐2/HT29‐MTX Co‐cultured Cell Lines: Permeabilities Via Diffusion, Inside‐ and Outside‐Directed Carrier‐Mediated Transport

Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability

Ismael J. Hidalgo, Thomas J. Raub, Ronald T. Borchardt · Gastroenterology · 1989 · 2.2K citations

Life Sciences, Cell Biology, Oncology +14

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) Cells

Per Artursson · Journal of Pharmaceutical Sciences · 1990 · 836 citations · Full text

Pharmacy, Pharmaceutics, Pharmacology +17

Physiology of the gastrointestinal tract

Harvey J. Dworken · Gastroenterology · 1987 · 643 citations

Life Sciences, Anatomy, Physiology +12

Caco-2 Cell Monolayers as a Model for Drug Transport Across the Intestinal Mucosa

Allen R. Hilgers, Robert A. Conradi, Philip S. Burton · Pharmaceutical Research · 1990 · 582 citations

Pharmacy, Pharmaceutics, Pharmacology +15