Construction and screening of 2-aryl benzimidazole library identifies a new antifouling and antifungal agent

Abstract

Library of 2-aryl benzimidazole core inspired from marine natural products, is identified and synthesized to explore antifouling/antifungal properties for the first time. Our results reveal that the 2-aryl substituent on the benzimidazole core had strong impact on their biological profile.