Expression of bone morphogenetic proteins (BMP), BMP receptors, and BMP associated proteins in human trabecular meshwork and optic nerve head cells and tissues.

Abstract

Members of the BMP family of genes, including BMPs, BMP receptors, and inhibitory BMP associated proteins are expressed in the human TM and ONH. These molecules may be involved in the normal formation and function of these tissues. Altered expression of members of this gene family may lead to functional changes in the TM and ONH. These genes and their respective signaling pathways merit further research to examine their possible role in glaucoma.