Detection of concanavalin A based on attenuated fluorescence resonance energy transfer between quantum dots and mannose-stabilized gold nanoparticles

Abstract

Highly sensitive biosensing of concanavalin A (Con A) has been developed based on the attenuation of FRET efficiency between amine-terminated quantum dots and mannose-stabilized Au nanoparticles in the presence of Con A, which inhibits the H-bonding formation of the QDs–AuNPs assembly, thereby causing the fluorescence recovery.