Peptide‐Nanotube Biochips for Label‐Free Detection of Multiple Pathogens

Abstract

Peptide nanotubes are integrated with microfabricated transducer arrays for bacterial detection. On each microelectrode of the array, circulating antibody-modified peptide nanotubes agglutinate bacteria as pathogen catchers and generate an impedance signal on the transducer. The pathogen microarray can detect as few as 102 cells of E. coli or S. typhi within one hour and the sensor chip can be easily reused for multiple measurements. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.