Publication | Closed Access
Catalytic Stereoselective Conjugate Addition of Oxindole to Electron‐Deficient Alkynes
24
Citations
27
References
2013
Year
Conventional OperationsDerivativesBut‐2‐ynedioate DerivativesEngineeringOrganic ChemistryCatalysisChemistryH ,9B HAsymmetric CatalysisSynthetic ChemistryEnantioselective SynthesisBiomolecular EngineeringElectron‐deficient Alkynes
Abstract A Z / E‐ selective and enantioselective conjugate addition of oxindoles to butyl but‐2‐ynedioate derivatives has been developed, providing a facile access to enantioenriched multifunctional olefins, which can be further converted into 3,3a‐ dihydro‐2 H ‐pyrrolo[3,4‐ c ]quinoline‐1,4(5 H ,9b H )‐dione derivatives via conventional operations.
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