HFE Cys282Tyr Homozygotes With Serum Ferritin Concentrations Below 1000 μg/L Are at Low Risk of Hemochromatosis†,‡

Abstract

Previously undiagnosed C282Y homozygotes with SF concentrations that remain below 1000 microg/L are at low risk of developing HH-associated signs and symptoms at an age when disease would be expected to have developed. These observations have implications for the management of C282Y homozygotes.