Heart · 1997 · 66 citations · 17 references
MedicineCardiologyClinical CardiologyInterventional CardiologyPreventive CardiologyAcute Coronary SyndromesCoronary AngioplastyCoronary Artery DiseaseIschemic Heart DiseasePercutaneous Coronary InterventionThrombolytic TherapyAcute Myocardial Infarction DiagnosisClinical Outcome MeasurementManagement Of High-risk Patients
OBJECTIVE: To investigate the feasibility of primary coronary angioplasty as a treatment option in patients with acute myocardial infarction after initial diagnosis in a local community hospital. SETTING: Referral centre for interventional treatment of coronary artery disease. METHODS: During a five year period, 520 candidates for primary coronary angioplasty were treated in our institution, 104 after transfer from a community hospital. The transferred patients and the non-transferred patients (n = 416) were compared with regard to baseline clinical characteristics, time interval from symptom onset to treatment, and clinical outcome at six months. RESULTS: In this setting, the influence of transportation on total ischaemic time was limited, and there was no difference in clinical outcome between the transferred and the non-transferred patients. Clinical outcome was mainly dependent on the indication for transfer. CONCLUSIONS: Safe and expedient transportation may facilitate the more widespread use of primary angioplasty in patients with acute myocardial infarction. A large randomised multicentre trial is needed to compare the relative merits of intravenous thrombolytic treatment in a local hospital with primary angioplasty after transfer in selected high risk patients with acute myocardial infarction.
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The GUSTO Angiographic Investigators · New England Journal of Medicine · 1993 · 1.9K citations · Full text
Medicine, Cardiology, Pharmacology +15
Joel M. Gore, Christopher B. Granger, Maarten L. Simoons et al. · Circulation · 1995 · 321 citations