Significance of increased right ventricular uptake on 99mTc-sestamibi SPECT in patients with coronary artery disease.

Abstract

Increased RV uptake, assessed from standard myocardial perfusion studies, can identify RV pressure overload among patients with CAD. In the absence of pulmonary or valvular heart disease, increased RV uptake (i.e., RV pressure overload) indicates significant backward failure, a variable with known significant negative prognostic implications.