Decreased Dopamine D2/D3‐Receptor Binding in Temporal Lobe Epilepsy: An [¹⁸F]Fallypride PET Study

Abstract

D2/D3-receptor binding is reduced at the pole and in lateral aspects of the epileptogenic temporal lobe in patients with mesial TLE and HS. This area might correspond to "the irritative zone," indicating that D2/D3 receptors might play a specific role in the pathophysiology of mesial TLE.