Dopaminergic Modulation of Probabilistic Reasoning and Overconfidence in Errors: A Double-Blind Study

Abstract

This is the first study to investigate the direct effects of dopaminergic drugs on reasoning biases. The JTC bias and overconfidence in errors showed a differential pattern of dopaminergic modulation, suggesting that they represent different facets of reasoning abnormalities that interact with each other to produce delusions in susceptible individuals.