Ultrabright and Bioorthogonal Labeling of Cellular Targets Using Semiconducting Polymer Dots and Click Chemistry

Abstract

All aboard! A facile conjugation method allows covalent linking of functional molecules to semiconducting polymer dots for bioorthogonal labeling of cellular targets. Targeting of the polymer dots to newly synthesized proteins and glycoproteins in mammalian cells by click chemistry is highly efficient and specific. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.