Targeted Bioimaging and Photodynamic Therapy Nanoplatform Using an Aptamer‐Guided G‐Quadruplex DNA Carrier and Near‐Infrared Light

Abstract

Target practice: A novel photodynamic therapy system has been constructed by taking advantage of the specific molecular recognition of an aptamer, loading capability of a G-quadruplex, and upconversion of nanoparticles using near-infrared (NIR) light. This system selectively delivers a photosensitizer to targeted cells and upon irradiation with NIR light demonstrates phototoxicity effects.