False-Positive <i>Histoplasma capsulatum</i> Gen-Probe Chemiluminescent Test Result Caused by a <i>Chrysosporium</i> Species

Abstract

We describe a case in which the Histoplasma capsulatum AccuProbe test displayed cross-reactivity with a respiratory isolate thought to be Histoplasma but not morphologically consistent with H. capsulatum. The isolate was later identified as the Chrysosporium anamorph of Nannizziopsis vriesii by sequence analysis and phenotypic data.