Prevalence of Sarcopenia and Predictors of Skeletal Muscle Mass in Nonobese Women Who Are Long-Term Users of Estrogen-Replacement Therapy

Abstract

Sarcopenia is as common in nonobese women who are long-term ERT users as in community-dwelling women not using ERT, suggesting that ERT does not protect against the muscle loss of aging. BMI, strength, and testosterone level contributed to appendicular skeletal mass in women. These data suggest that interventions to target nutrition, strength training, and testosterone replacement should be further investigated for their role in preventing muscle loss with age.