Concepedia

Selection of Retapamulin, a Novel Pleuromutilin for Topical Use

Stephen Rittenhouse, Sanjoy Kanti Biswas, John P. Broskey, Lynn McCloskey, Terrance Moore, Sandra Y. Vasey, Joshua M. West, Magdalena Zalacaín, Rimma Zonis, David Payne

Antimicrobial Agents and Chemotherapy · 2006 · 91 citations · 5 references

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Abstract

The in vitro activity of retapamulin was determined and compared to that of topical and community antibiotics. The MIC(90)s of retapamulin against Staphylococcus aureus and Streptococcus pyogenes were 0.12 microg/ml and 0.016 microg/ml, respectively. Retapamulin has a low propensity to select resistance and produces an in vitro postantibiotic effect.

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Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically

Mary Jane Ferraro · 2000 · 16.9K citations

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Antimicrobial resistance: priorities for action

R. Wise · Journal of Antimicrobial Chemotherapy · 2002 · 309 citations · Full text

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Biochemical Characterization of the Interactions of the Novel Pleuromutilin Derivative Retapamulin with Bacterial Ribosomes

Kang Yan, Lenore Madden, Anthony E. Choudhry et al. · Antimicrobial Agents and Chemotherapy · 2006 · 120 citations · Full text

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Postantibiotic and post-beta-lactamase inhibitor effects of amoxicillin plus clavulanate

Christine E. Thorburn, S J Molesworth, R. Sutherland et al. · Antimicrobial Agents and Chemotherapy · 1996 · 47 citations · Full text

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Use of the Surgical Wound Infection Model To Determine the Efficacious Dosing Regimen of Retapamulin, a Novel Topical Antibiotic

Stephen Rittenhouse, Christine M. Singley, Jennifer L. Hoover et al. · Antimicrobial Agents and Chemotherapy · 2006 · 46 citations · Full text

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