Enlargement of atrophy and visual acuity loss in the geographic atrophy form of age-related macular degeneration

Abstract

Geographic atrophy is associated with a significant decline in VA over time in many eyes. Areas of atrophy continue to enlarge over time, even when already large at baseline. The combination of reduced VA with enlargement of atrophy, occurring bilaterally in most patients, can lead to significant impairment of visual function.