SOSTDC1 down-regulation of expression involves CpG methylation and is a potential prognostic marker in gastric cancer

Repression of genes by DNA methylation depends on CpG density and promoter strength: evidence for involvement of a methyl‐CpG binding protein.

Joan Boyes, Adrian Bird · The EMBO Journal · 1992 · 480 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

William M. Grady, Joseph Willis, Parry Guilford et al. · Nature Genetics · 2000 · 449 citations

Medicine, Genetics, Molecular Genetics +16

Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line

Einav Nili Gal‐Yam, Gerda Egger, Leo Iniguez et al. · Proceedings of the National Academy of Sciences · 2008 · 396 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot

Johanna Laurikkala, Yoshiaki Kassai, Leila Pakkasjärvi et al. · Developmental Biology · 2003 · 265 citations

Dentistry, Craniofacial Biology, Oral Biology +9

Inhibition of Wnt signaling by Wise (Sostdc1) and negative feedback from Shh controls tooth number and patterning

Youngwook Ahn, Brian W. Sanderson, Ophir D. Klein et al. · Development · 2010 · 213 citations · Full text

Life Sciences, Developmental Biology, Oral Biology +17