Oral and Maxillofacial Pathology: MMP and TIMP gene expression in head and neck squamous cell carcinomas and adjacent tissues

Abstract

Specific MMP (MMP-3, -7, -10, -14) and TIMP-3 transcripts observed in head and neck squamous cell carcinomas compared to their frequency in specimens of matching tissues provide important information about expression of extracellular matrix degrading enzymes and their tissue inhibitors in head and neck carcinomas.