Nature · 2013 · 958 citations · 29 references
MedicineGeneticsMolecular GeneticsChromatin BiologyEpigeneticsMedical GeneticsChromatinCongenital Heart DiseaseCongenital Heart Disease GeneticsGenetic DisordersHistone ModificationsMendelian Cardiovascular DisordersCardiac Development GeneticsCardiac Developmental DefectsCongenital Heart Defect MutationsCongenital Heart Disease PathophysiologyCongenital Valvular Heart Disease
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A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells
B Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie et al. · Cell · 2006 · 5.4K citations · Full text
Rate of de novo mutations and the importance of father’s age to disease risk
Augustine Kong, Michael L. Frigge, Gísli Másson et al. · Nature · 2012 · 2.3K citations
Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
Brian J. O’Roak, Laura Vives, Santhosh Girirajan et al. · Nature · 2012 · 2.2K citations · Full text
De novo mutations revealed by whole-exome sequencing are strongly associated with autism
Stephan Sanders, Michael T. Murtha, Abha R. Gupta et al. · Nature · 2012 · 2.2K citations
Patterns and rates of exonic de novo mutations in autism spectrum disorders
Benjamin M. Neale, Yan Kou, Li Liu et al. · Nature · 2012 · 1.8K citations · Full text