One Thousand Consecutive Primary Liver Transplants Under Tacrolimus Immunosuppression: A 17- to 20-Year Longitudinal Follow-Up

Abstract

The overall 20-year actuarial patient and graft survivals were 35.8% and 32.6%, respectively, with significantly better survival among children. Age-related complications, recurrence of primary disease, and malignancy were the major causes of late graft loss. Graft loss related to immunologic reasons was rare. The prevention of recurrent disease and newer immunosuppressive regimen will further improve these results.