C‐Nitroso compounds. Part XXXIV. Reaction of α‐chloronitroso compounds with methyl and phenyl Grignard reagents. A convenient synthesis of α,α‐dialkyl‐N‐methyl and ‐N‐phenyl nitrones

Abstract

Abstract The α‐chloronitroso compounds 1a–1f were made to react with methyl and phenyl Grignard reagents. N‐methyl and N‐phenyl substituted ketonitrones 2 and 3 were obtained in 48‐78% yield. The structure of these labile nitrones is based on their spectroscopic properties and on the formation of characteristic 1,3‐cycloadducts with phenylisocyanate.