Bioinformatics · 2015 · 113 citations · 7 references
Life SciencesBioinformaticsGeneticsMedical GeneticsNeuropsychiatrySubstance Use DisordersBehavioral GenomicsEtiology Of Mental DisordersGene-disease Association MiningNeuropsychiatric GeneticsPsychiatric GeneticsAssociation Network AnalysisDepression GeneticsEtiology Of Psychotic DisordersMajor DepressionMajor Depressive Disorder GeneticsNetwork-based Association AnalysisPsychiatric GenomicsSubstance Use Disorder Genetics
UNLABELLED: PsyGeNET (Psychiatric disorders and Genes association NETwork) is a knowledge platform for the exploratory analysis of psychiatric diseases and their associated genes. PsyGeNET is composed of a database and a web interface supporting data search, visualization, filtering and sharing. PsyGeNET integrates information from DisGeNET and data extracted from the literature by text mining, which has been curated by domain experts. It currently contains 2642 associations between 1271 genes and 37 psychiatric disease concepts. In its first release, PsyGeNET is focused on three psychiatric disorders: major depression, alcohol and cocaine use disorders. PsyGeNET represents a comprehensive, open access resource for the analysis of the molecular mechanisms underpinning psychiatric disorders and their comorbidities. AVAILABILITY AND IMPLEMENTATION: The PysGeNET platform is freely available at http://www.psygenet.org/. The PsyGeNET database is made available under the Open Database License (http://opendatacommons.org/licenses/odbl/1.0/). CONTACT: lfurlong@imim.es SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
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Grand challenges in global mental health
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