SRY-directed DNA Bending and Human Sex Reversal: Reassessment of a Clinical Mutation Uncovers a Global Coupling between the HMG Box and its Tail

A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif

Andrew Sinclair, Philippe Berta, Mark S. Palmer et al. · Nature · 1990 · 3.3K citations

Life Sciences, Genetics, Molecular Genetics +13

Male development of chromosomally female mice transgenic for Sry

Peter Koopman, John Gubbay, Nigel Vivian et al. · Nature · 1991 · 2.2K citations

Life Sciences, Developmental Biology, Genetics +14

A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes

John Gubbay, Jérôme Collignon, Peter Koopman et al. · Nature · 1990 · 1.7K citations

Life Sciences, Genetics, Molecular Genetics +13

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9

Thomas Wagner, Jutta Wirth, Jobst Meyer et al. · Cell · 1994 · 1.6K citations

Life Sciences, Genetics, Molecular Genetics +15

Genetic evidence equating SRY and the testis-determining factor

Philippe Berta, J Hawkins, Andrew Sinclair et al. · Nature · 1990 · 989 citations

Life Sciences, Genetics, Molecular Genetics +9