22-Oxacalcitriol prevents progression of endothelial dysfunction through antioxidative effects in rats with type 2 diabetes and early-stage nephropathy - Concepedia

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22-Oxacalcitriol prevents progression of endothelial dysfunction through antioxidative effects in rats with type 2 diabetes and early-stage nephropathy

61

Citations

40

References

2012

Year

Michinori Hirata, Kenichi Serizawa, Ken Aizawa, Kenji Yogo, Yoshihito Tashiro, Satoshi Takeda, Yoshiyuki Moriguchi, Koichi Endo, Masafumi Fukagawa

Nephrology Dialysis Transplantation

Abstract

In DM rats, OCT improved endothelial dysfunction, at least in part, by suppressing ROS generation through p22(phox) expression, which might contribute to improving eNOS uncoupling.

References

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