¹⁸F-FLT PET/CT for Early Response Monitoring and Dose Escalation in Oropharyngeal Tumors

Abstract

(18)F-FLT is a promising PET tracer for imaging tumor cell proliferation in head and neck carcinomas. Signal changes in (18)F-FLT PET precede volumetric tumor response and are therefore suitable for early response assessment. Definition of tumor subvolumes with high proliferative activity and dose escalation to these regions are technically feasible.